for fuck’s sake, you illiterate casuals
systemic: happening to a whole system. a hormone might work systemically through your body, as opposed to locally (e.g. in your leg). IGF-1 LR3 is thought to be a mostly systemic hormone; IGF-1 DES is thought to be mostly local. it does not mean “done by systems” or “done by institutions”. there is no such thing as systematic or institutional hormones.
systematic: done as a system, such as by a method or process. a system has structure and boundaries; it’s an interacting or interdependent group of things forming an integrated whole. if you don’t know this, you are not above wikipedia. a frozen yogurt shop might systematically integrate a process applying to all employees, such as evaluation forms. however, in ordinary cases, a frozen yogurt shop is not an institution. it does not systemically integrate these forms, because these forms don’t apply to all aspect of the shop, like when the owner orders ingredients or files taxes.
institutional: done by institutions. if the university of texas decides that everyone can have free coffee at 9AM every monday, this is an institutional act. meanwhile, if the starbucks next to the university of texas decides to give you free coffee for whatever reason, this is the business’s choice, but unconnected from the university of texas. the choice of the university is not systemic, because it does not affect all levels of the university; the free coffee does not interrupt classes, to give one trivial example.
for more like this, see “semantic precision exercises.”
there is no excuse for ignorance with search engines on your phone. I have written this article in mostly lowercase because this is something you should know already, and you don’t deserve the effort of capitalization.